Tirzepatide
Also known as: GIP/GLP-1 dual agonist
Pricing — All Vial Sizes
| Vial Size | Kit Price | Per Vial | Per mg | Stock |
|---|---|---|---|---|
| 5 mg← selected | $40 | $4.00 | $0.80/mg | ○ Out of Stock |
| 10 mg | $60 | $6.00 | $0.60/mg | ○ Out of Stock |
| 15 mg | $80 | $8.00 | $0.53/mg | ○ Out of Stock |
| 20 mg | $90 | $9.00 | $0.45/mg | ○ Out of Stock |
| 30 mg | $100 | $10.00 | $0.33/mg | ○ Out of Stock |
| 40 mg | $135 | $13.50 | $0.34/mg | ○ Out of Stock |
| 60 mg | $200 | $20.00 | $0.33/mg | ○ Out of Stock |
| 70 mg | $220 | $22.00 | $0.31/mg | ○ Out of Stock |
| 120 mg | $320 | $32.00 | $0.27/mg | ○ Out of Stock |
Last changed: 4h ago
Summary
Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. In clinical research it has demonstrated significant reductions in body weight and glycemic markers, with effects exceeding those of GLP-1 mono-agonists in head-to-head comparisons. It mimics endogenous incretin hormones released after meals.
Think of it as a supercharged appetite suppressant. After you eat, your body releases hormones that tell you to stop eating and signal your pancreas to release insulin. Tirzepatide mimics two of those hormones at once — making it more effective than drugs that only mimic one. It's produced some of the largest weight losses ever recorded in a clinical drug trial.
Mechanism of Action↓
Tirzepatide binds and activates both GIP (GIPR) and GLP-1 (GLP-1R) receptors with near-equal potency. Activation of these receptors amplifies insulin secretion in a glucose-dependent manner, suppresses glucagon, slows gastric emptying, and reduces appetite via central and peripheral signaling pathways (hypothalamic arcuate nucleus). The dual agonism appears synergistic for adiposity reduction.
Half-life: ~5 days (terminal elimination, once-weekly dosing in clinical trials)
Research Dosing Ranges↓
2.5 mg – 15 mg
Once weekly subcutaneous injection
Escalation protocol: 2.5 mg × 4 weeks, then 5 mg × 4 weeks, up to 15 mg. Research subjects are typically titrated to tolerate GI effects.
Reconstitution Guidance↓
BAC water: 3 mL
Resulting concentration: 3.3 mg/mL (for 10 mg vial)
Typical dose: 75 units on U-100 syringe = 2.5 mg
Add 3 mL sterile BAC water to 10 mg lyophilized vial. Mix by gentle rotation; do not shake.
Storage & Stability↓
Lyophilized: store at 2–8°C or room temp (<25°C) away from light. Reconstituted: refrigerate, use within 28 days.
Known Side Effects / Contraindications↓
Nausea, vomiting, diarrhea (most common, dose-dependent), constipation, decreased appetite, injection site reactions. GI symptoms typically diminish with titration. Rare: pancreatitis signal in surveillance data.
Price History
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Change History
Reconstitution Calculator
Concentration
1.67 mg/mL
Volume per dose
1500.0 µL
U-100 units
150.0 units
Doses per vial
2.0
Cost per dose
$2.00(based on kit price)
Show math
Concentration: 5 mg ÷ 3 mL = 1.67 mg/mL (1667 µg/mL)
Dose needed: 2500 µg = 2.5000 mg
Volume per dose: 2.5000 mg ÷ 1.67 mg/mL = 1.5000 mL
On U-100 syringe: 1500.0 µL = 150.0 units
Total doses in vial: 5 mg ÷ 2.5000 mg = 2.0 doses
⚠ Research Reference Only
All dosage information, mechanisms, and research data on this site are provided for educational and research reference purposes only. This is not medical advice. These compounds are not approved for human use or consumption. Always consult a licensed medical professional and comply with your local regulations.