PT-141
Also known as: Bremelanotide
Pricing — All Vial Sizes
| Vial Size | Kit Price | Per Vial | Per mg | Stock |
|---|---|---|---|---|
| 10 mg← selected | $65 | $6.50 | $0.65/mg | ○ Out of Stock |
| 14110 mg | $90 | $9.00 | $0.00/mg | ○ Out of Stock |
Last changed: 4h ago
Summary
PT-141 (bremelanotide) is a cyclic heptapeptide melanocortin analogue derived from Melanotan II. It activates MC3R and MC4R centrally to produce sexual arousal in both men and women. An approved intranasal formulation (Vyleesi) is used for hypoactive sexual desire disorder (HSDD) in premenopausal women.
PT-141 works on the brain to create sexual desire — unlike Viagra or Cialis, which only work on blood vessels. This means it's effective in both men and women, and it produces psychological arousal, not just a physical response. A milder intranasal version (Vyleesi) is FDA-approved for women with low libido. The injectable version used in research is more potent. Nausea is the main side effect to manage — start low.
Mechanism of Action↓
MC4R agonism in the brain's limbic system (particularly the medial preoptic area) mediates sexual arousal and erectile/genital blood flow independently of the NO-cGMP pathway. This distinguishes it from PDE5 inhibitors and makes it active in both sexes.
Half-life: ~2–3 hours
Research Dosing Ranges↓
1–2 mg per injection (0.5 mg for first-time users)
As needed, 1–2 hours before activity; not for daily use
Community consensus: 1–1.5 mg is the sweet spot for most users. Start at 0.5 mg to assess nausea response. Do not exceed 2 mg — stronger side effects without added benefit. Not recommended more than 2×/week.
Reconstitution Guidance↓
BAC water: 3 mL
Resulting concentration: 3.33 mg/mL (for 10 mg vial)
Typical dose: 30–45 units on U-100 syringe = 1–1.5 mg
Add 3 mL BAC water to 10 mg vial → 3.33 mg/mL. 1 mg dose = 300 µL = 30 units U-100.
Storage & Stability↓
Refrigerate. Reconstituted: use within 28 days.
Known Side Effects / Contraindications↓
Nausea (most common), flushing, headache, transient hypertension, hyperpigmentation with repeated use. Nausea may be reduced with antiemetics 30 min pre-dose.
Price History
Showing history for the 10 mg vial.
Change History
Reconstitution Calculator
Concentration
3.33 mg/mL
Volume per dose
150.0 µL
U-100 units
15.0 units
Doses per vial
20.0
Cost per dose
$0.33(based on kit price)
Show math
Concentration: 10 mg ÷ 3 mL = 3.33 mg/mL (3333 µg/mL)
Dose needed: 500 µg = 0.5000 mg
Volume per dose: 0.5000 mg ÷ 3.33 mg/mL = 0.1500 mL
On U-100 syringe: 150.0 µL = 15.0 units
Total doses in vial: 10 mg ÷ 0.5000 mg = 20.0 doses
⚠ Research Reference Only
All dosage information, mechanisms, and research data on this site are provided for educational and research reference purposes only. This is not medical advice. These compounds are not approved for human use or consumption. Always consult a licensed medical professional and comply with your local regulations.