NAD+
Also known as: Nicotinamide Adenine Dinucleotide
Pricing — All Vial Sizes
| Vial Size | Kit Price | Per Vial | Per mg | Stock |
|---|---|---|---|---|
| 100 mg← selected | $120 | $12.00 | $0.12/mg | ○ Out of Stock |
| 500 mg | $85 | $8.50 | $0.02/mg | ○ Out of Stock |
| 1000 mg | $130 | $13.00 | $0.01/mg | ○ Out of Stock |
Last changed: 4h ago
Summary
NAD+ (nicotinamide adenine dinucleotide) is a critical coenzyme involved in hundreds of metabolic reactions. Intracellular NAD+ levels decline with age. Parenteral NAD+ supplementation is studied for energy metabolism, sirtuin activation, DNA repair via PARP enzymes, and neuroprotection.
Every cell in your body uses NAD+ to produce energy and repair damaged DNA, but levels drop by roughly half between your 20s and 50s. Injectable NAD+ bypasses the digestive conversion that limits oral supplements and delivers it directly to the bloodstream. People often report a dramatic energy boost during IV infusions — along with intense but temporary flushing and muscle cramping if infused too fast.
Mechanism of Action↓
NAD+ serves as an electron carrier in redox reactions (glycolysis, TCA cycle, oxidative phosphorylation). Also the substrate for sirtuins (SIRT1-7) — NAD+-dependent deacylases that regulate aging pathways, mitochondrial biogenesis, and stress responses. PARP1/2 consume NAD+ for DNA repair.
Half-life: ~1–2 hours (intracellular); IV infusion achieves rapid systemic elevation
Research Dosing Ranges↓
250–1000 mg
IV infusion or subcutaneous injection
IV: 250–1000 mg slow infusion over 1–4 hours. SC: 25–100 mg. Must be given slowly — rapid IV NAD+ causes intense flushing, chest tightness.
Reconstitution Guidance↓
BAC water: 3 mL
Resulting concentration: mg/mL depends on vial size
Reconstitute in sterile saline or BAC water. For SC injections, keep volumes small. Use reconstituted vials promptly — NAD+ degrades in solution.
Storage & Stability↓
Refrigerate or freeze lyophilized. Reconstituted: use immediately or within 24 hours.
Known Side Effects / Contraindications↓
IV: intense flushing, nausea, muscle cramping, pressure in chest (rate-dependent — must infuse slowly). SC: injection site discomfort. Generally resolves with rate reduction.
Price History
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Reconstitution Calculator
Concentration
33.33 mg/mL
Volume per dose
7.5 µL
U-100 units
0.8 units
Doses per vial
400.0
Cost per dose
$0.03(based on kit price)
Show math
Concentration: 100 mg ÷ 3 mL = 33.33 mg/mL (33333 µg/mL)
Dose needed: 250 µg = 0.2500 mg
Volume per dose: 0.2500 mg ÷ 33.33 mg/mL = 0.0075 mL
On U-100 syringe: 7.5 µL = 0.8 units
Total doses in vial: 100 mg ÷ 0.2500 mg = 400.0 doses
⚠ Research Reference Only
All dosage information, mechanisms, and research data on this site are provided for educational and research reference purposes only. This is not medical advice. These compounds are not approved for human use or consumption. Always consult a licensed medical professional and comply with your local regulations.