KPV
Also known as: α-MSH(11-13)
Pricing — All Vial Sizes
| Vial Size | Kit Price | Per Vial | Per mg | Stock |
|---|---|---|---|---|
| 10 mg← selected | $70 | $7.00 | $0.70/mg | ● In Stock |
Last changed: Jun 10
Summary
KPV is the C-terminal tripeptide of α-MSH (Lys-Pro-Val). It retains anti-inflammatory activity of the parent peptide while being much smaller. Studied for inflammatory bowel disease, wound healing, and skin inflammation. Can be delivered orally in nano-formulations due to small size.
KPV is just three amino acids long — the tail end of the anti-inflammatory hormone α-MSH. It's small enough that when encapsulated in nanoparticles, it can survive the digestive system and reach the gut lining intact, making it a candidate for oral treatment of Crohn's disease and ulcerative colitis. Injected, it reduces systemic inflammation. One of the smallest active peptides in research.
Mechanism of Action↓
Binds melanocortin receptors (MC1R, MC3R) to inhibit NF-κB activation and reduce pro-inflammatory cytokine production (TNF-α, IL-1β, IL-6). Also acts intracellularly on inflammatory signaling pathways independent of membrane receptor binding.
Half-life: ~1–2 hours
Research Dosing Ranges↓
100–500 µg per dose
Once or twice daily subcutaneous
Gut inflammation models use oral nanoparticle formulations. Systemic SC doses are less established.
Reconstitution Guidance↓
BAC water: 1 mL
Resulting concentration: mg/mL depends on vial size
Standard BAC water reconstitution.
Storage & Stability↓
Refrigerate. Use within 14 days of reconstitution.
Known Side Effects / Contraindications↓
Very limited. Well tolerated in animal studies.
Price History
Change History
Reconstitution Calculator
Concentration
3.33 mg/mL
Volume per dose
75.0 µL
U-100 units
7.5 units
Doses per vial
40.0
Cost per dose
$0.17(based on kit price)
Show math
Concentration: 10 mg ÷ 3 mL = 3.33 mg/mL (3333 µg/mL)
Dose needed: 250 µg = 0.2500 mg
Volume per dose: 0.2500 mg ÷ 3.33 mg/mL = 0.0750 mL
On U-100 syringe: 75.0 µL = 7.5 units
Total doses in vial: 10 mg ÷ 0.2500 mg = 40.0 doses
⚠ Research Reference Only
All dosage information, mechanisms, and research data on this site are provided for educational and research reference purposes only. This is not medical advice. These compounds are not approved for human use or consumption. Always consult a licensed medical professional and comply with your local regulations.