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Skin & Cosmetic● In Stock

GHK-Cu

Also known as: Copper tripeptide-1, GHK

Pricing — All Vial Sizes

1 kit = 10 vials. Per-mg price calculated across the full kit (vial mg × 10 vials).Click a row to load it in the calculator →
Vial SizeKit PricePer VialPer mgStock
50 mg← selected$50$5.00$0.10/mg● In Stock
100 mg$70$7.00$0.07/mg● In Stock

Last changed: 20d ago

Summary

GHK-Cu is a naturally occurring human tripeptide (Gly-His-Lys) complexed with copper(II). Plasma concentrations decline with age. In research it promotes collagen synthesis, angiogenesis, wound healing, and anti-inflammatory effects. Widely studied in dermatology for skin remodeling.

GHK-Cu is a tiny copper-binding peptide your body naturally produces — but levels drop significantly with age. It activates genes that build collagen and elastin (the structural proteins that keep skin firm), grows new blood vessels to wounds, and calms inflammation. Found in many high-end skin creams, but injectable research uses suggest systemic effects beyond just the skin.

Mechanism of Action

The copper-chelating tripeptide activates TGF-β signaling to stimulate collagen I, III, and VI synthesis. Upregulates VEGF and promotes angiogenesis. Activates proteasome activity for removal of damaged proteins. Antioxidant and anti-inflammatory via downregulation of NF-κB pathway.

Half-life: ~30 minutes (plasma); topical application has sustained local effects

Research Dosing Ranges
⚠ Research reference only — not medical advice, not for human use.

1–5 mg per dose (subcutaneous) or topical application

Subcutaneous: once or twice daily. Topical: 2× daily

Topical: 0.1–1% concentrations. Subcutaneous: 1–2 mg/dose. Facial injection research uses very low doses.

Reconstitution Guidance

BAC water: 1 mL

Resulting concentration: mg/mL depends on vial size

Reconstitute in sterile water. Do not use with peptides that may chelate copper differently.

Storage & Stability

Room temp for lyophilized. Refrigerate reconstituted. Use within 14–28 days.

Known Side Effects / Contraindications
⚠ Research reference only — not medical advice, not for human use.

Topical: blue-green tint at injection site (transient, copper). Generally very well tolerated.

References

Price History

Showing history for the 50 mg vial.

Change History

20d agoGHK-CU50mgstockout_of_stock → in_stock
28d agoGHK-CU50mgstockin_stock → out_of_stock
Jun 10GHK-CU100mgstockout_of_stock → in_stock
Jun 2GHK-CU50mgstockout_of_stock → in_stock
Jun 2GHK-CU100mgstockin_stock → out_of_stock
May 26GHK-CU100mgstockout_of_stock → in_stock
May 26GHK-CU100mgstockout_of_stock → in_stock
May 26GHK-CU100mgstockin_stock → out_of_stock
May 26GHK-CU100mgstockout_of_stock → in_stock
May 26GHK-CU100mgstockin_stock → out_of_stock
May 19GHK-CU50mgnew{"price":50,"stock":"out_of_stock"}
May 19GHK-CU100mgnew{"price":70,"stock":"out_of_stock"}

Reconstitution Calculator

Concentration

16.67 mg/mL

Volume per dose

30.0 µL

U-100 units

3.0 units

Doses per vial

100.0

Cost per dose

$0.05(based on kit price)

Show math

Concentration: 50 mg ÷ 3 mL = 16.67 mg/mL (16667 µg/mL)

Dose needed: 500 µg = 0.5000 mg

Volume per dose: 0.5000 mg ÷ 16.67 mg/mL = 0.0300 mL

On U-100 syringe: 30.0 µL = 3.0 units

Total doses in vial: 50 mg ÷ 0.5000 mg = 100.0 doses

⚠ Research Reference Only

All dosage information, mechanisms, and research data on this site are provided for educational and research reference purposes only. This is not medical advice. These compounds are not approved for human use or consumption. Always consult a licensed medical professional and comply with your local regulations.